| January 1 | Juw Dekama elected potentate of Frisia |
| January 25 | Alfonso II replaces his father as king of Naples |
| May 3 | Columbus discovers Jamaica |
| May 3 | Jamaica discovered by Columbus; he names it "St. Iago" |
| May 4 | Christopher Columbus lands in Jamaica |
| May 5 | On 2nd voyage to New World, Christopher Columbus sights Jamaica |
| June 7 | Treaty of Tordesillas, Spain and Portugal divide America |
| November 8 | Uprising against Piero de' Medici in Florence Italy |
| November 9 | Family de' Medici become rulers of Florence |
| November 18 | French king Charles VIII occupies Florence |
