| January 1 | Charles II Stuart crowned king of Scotland |
| February 6 | Cardinal Mazarin flees Paris |
| February 13 | Flemish missionary Joris van Geel departs to Congo |
| March 5 | South Sea dike in Amsterdam breaks after storm |
| March 31 | Great earthquake at Cuzco Peru |
| July 24 | Anthony Johnson, a free black, receives grant of 250 acres in Va |
| August 13 | Litchfield, CT founded |
| September 3 | Battle at Worcester-Oliver Cromwell destroys English royalists |
| October 9 | English parliament proclaims Navigation Act off |
| October 17 | Future King Charles II flees from England |
| October 27 | English troops occupy Limerick Ireland |
| November 7 | King Louis XIV of France (13) declarer of full age |
| December 24 | John van Riebeeck departs to Cape of Good Hope |
| December 25 | Massachusetts General Court ordered a fine (five shillings) for "observing any such day as Christmas" |
