| January 11 | Ferdinand VI of Spain and Pope Benedictus XIV sign concord |
| March 17 | 1st official St. Patrick's Day |
| March 25 | Voltaire leaves the court of Frederik II of Prussia |
| April 5 | British Museum forms and opens in 1759 |
| May 6 | French King Louis XV observes transit of Mercury at Mendon Castle |
| May 9 | King Louis XV disbands French parliament |
| May 29 | Joseph Haydns "Krumme Teufel," premieres |
| June 13 | Austria, England and Modena sign secret military treaty |
| July 7 | English parliament grants Jewish English citizenship |
| July 18 | Lemuel Haynes, escapes from slave holder in Framingham Mass |
| August 4 | George Washington becomes a master mason |
| September 9 | 1st steam engine arrives in U.S. colonies |
| September 22 | Pangeran Gusti installed as sultan of Banten |
| November 30 | Benjamin Franklin receives Godfrey Copley-Penny |
