| January 11 | Frisia bans Voltaires "Traite sur la tolerance" |
| January 16 | Charles Messier catalogs M41 (galactic cluster in Canis Major) |
| March 22 | Stamp Act passed; 1st direct British tax on colonists |
| March 24 | Britain enacts Quartering Act, required colonists to provide temporary housing to British soldiers |
| May 3 | 1st U.S. medical college opens in Philadelphia |
| May 7 | Adm Nelsons sailboat HMS Victory runs aground |
| May 29 | Patrick Henry historic speech against the Stamp Act, answering a cry of "Treason!" with, "If this be treason, make the most of it!" |
| August 14 | Mass colonists challenge British rule by an Elm (Liberty Tree) |
| October 7 | Stamp Act Congress convenes in New York |
| October 19 | Stamp Act Congress met in New York, wrote declaration of rights and liberties |
| November 1 | Stamp Act goes into effect in British colonies |
| November 23 | People of Frederick County Md refuse to pay England's Stamp tax |
