| January 16 | Godert baron van der de Capellen becomes governor of Dutch-Indies |
| January 28 | Sir Stamford Raffles 1st lands in Singapore |
| February 6 | Sir Thomas Stamford Raffles founds freeport harbor Singapore |
| February 22 | Spain renounces claims to Oregon Country, Florida (Adams-Onis Treaty) |
| February 28 | 1st public performance of a Schubert song, "Schafers Klageleid" |
| March 2 | Territory of Arkansas organized |
| March 2 | U.S. passed its 1st immigration law |
| April 2 | 1st successful agricultural journal ("American Farmer") begins |
| April 26 | Odd Fellows Lodge forms |
| May 21 | 1st bicycles (swift walkers) in U.S. introduced in New York City |
| May 22 | 1st steam propelled vessel to cross Atlantic (Savannah leaves Ga) |
| June 12 | Dutch colonial troops driven out of Palembang Sumatra |
| June 20 | 320 ton Savannah becomes 1st steamship to cross any ocean (Atlantic) |
| July 3 | 1st savings bank in U.S. (Bank of Savings in New York City) opens its doors |
| July 4 | William Herschel makes last telescopic observation of 1819 comet |
| August 2 | 1st parachute jump in U.S. |
| August 7 | Battle of Boyaca; Bolivar defeats Spanish in Colombia |
| August 16 | Manchester Massacre: English police charge unemployed demonstrators |
| September 6 | Thomas Blanchard patents lathe |
| September 17 | 1st whaling ship arrives in Hawaii |
| October 22 | 1st ship sails by Erie-channel (Rome-Utica) |
| December 14 | Alabama admitted to Union as 22nd state |
| December 17 | Congress of Angostura establishes Colombia's independence from Spain |
